Thermo Fisher Scientific HERPUD1 Monoclonal Antibody (OTI1A2), TrueMAB
HERPUD1 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보관. 연구용으로 ER 스트레스 및 UPR 관련 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:400–1:4,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human HERPUD1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HERPUD1 is involved in the endoplasmic reticulum (ER) stress response, including unfolded protein response (UPR) and ER-associated protein degradation (ERAD).
Its expression is induced by UPR, and the protein contains an N-terminal ubiquitin-like domain that may interact with the ERAD system.
HERPUD1 interacts with presenilin proteins and can increase amyloid-beta levels upon overexpression.
Alternative splicing generates multiple transcript variants with potentially distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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