Thermo Fisher Scientific SUZ12 Monoclonal Antibody (3D10)
SUZ12 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Human 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- MA515733
- 판매단위
- pk
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Thermo Fisher Scientific SUZ12 Monoclonal Antibody (3D10)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D10 |
| Immunogen | Purified recombinant fragment of human SUZ12 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10979095 |
Product Specific Information
MA5-15733 targets SUZ12 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The MA5-15733 immunogen is a purified recombinant fragment of human SUZ12 expressed in E. coli.
MA5-15733 detects SUZ12 with a predicted molecular weight of approximately 83.1 kDa.
Target Information
SUZ12 (polycomb protein SUZ12) is a zinc finger gene identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma.
Recombination of these breakpoints results in the fusion of this gene and JAZF1.
SUZ12 is also a component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target genes.
The encoded protein contains a zinc finger domain at the C-terminus of the coding region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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