Thermo Fisher Scientific SUZ12 Monoclonal Antibody (2C11)
인간 SUZ12 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체. Western blot, ICC/IF, ELISA에 사용 가능. 비결합형 액상 형태이며 장기 보관은 -20°C 권장. 연구용으로만 사용.
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- MA515732
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C11 |
| Immunogen | Purified recombinant fragment of human SUZ12 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10979521 |
Product Specific Information
MA5-15732 targets SUZ12 in indirect ELISA, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human SUZ12 expressed in E. coli.
MA5-15732 detects SUZ12 with a predicted molecular weight of approximately 83.1 kDa.
Target Information
SUZ12 (polycomb protein SUZ12) is a zinc finger gene identified at the breakpoints of a recurrent chromosomal translocation in endometrial stromal sarcoma. The recombination of these breakpoints results in fusion of SUZ12 and JAZF1 genes.
SUZ12 is a component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of target genes. The encoded protein contains a zinc finger domain in the C-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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