Thermo Fisher Scientific Valproic Acid Monoclonal Antibody (VP10-234.5)
Valproic acid에 특이적인 단클론 항체로 ELISA에 적합. Mouse IgG1 형식이며, Protein A로 정제된 액상 형태. PBS(pH 7.4) 버퍼에 보존제 없이 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VP10-234.5 |
| Immunogen | Valproic acid, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1088195 |
Product Specific Information
MA1-10767 detects Valproic Acid.
This antibody has been successfully used in ELISA applications.
The immunogen is Valproic acid conjugated to KLH.
Target Information
Valproic acid, valproate sodium, and divalproex are anticonvulsants used to control seizures in epilepsy treatment.
Valproic acid also relieves histone deacetylases (HDACs)-dependent transcriptional repression, causing hyperacetylation of histones in cultured cells and in vivo.
It inhibits HDAC activity by binding to the catalytic center of HDACs and induces differentiation of carcinoma cells, hematopoietic progenitor cells, and leukemic blasts.
Furthermore, tumor growth and metastasis formation are significantly reduced in animal models.
Valproic acid may serve as an effective drug for cancer therapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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