Thermo Fisher Scientific Valproic Acid Monoclonal Antibody (VP10-115.2)
Valproic acid를 검출하는 Mouse IgG1 단클론 항체로 ELISA에 적합합니다. KLH에 결합된 Valproic acid로 면역화된 항체이며, 1.0 mg/mL 농도의 액상 형태로 제공됩니다. 단백질 G로 정제되었으며, -20°C에서 보관 권장됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Valproic Acid Monoclonal Antibody (VP10-115.2)
Applications
- ELISA (ELISA)
Tested Dilution: 1–10 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VP10-115.2 |
| Immunogen | Valproic acid conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1088193 |
Product Specific Information
MA1-10765 detects Valproic Acid.
MA1-10765 has been successfully used in ELISA applications.
The MA1-10765 immunogen is Valproic acid conjugated to KLH.
Target Information
Valproic acid, valproate sodium, and divalproex belong to the group of anticonvulsant medicines used to control certain types of seizures in epilepsy treatment.
Valproic acid also relieves histone deacetylases (HDACs)-dependent transcriptional repression and induces hyperacetylation of histones in cultured cells and in vivo.
It inhibits HDAC activity in vitro, likely by binding to the catalytic center of HDACs.
Importantly, valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells, and leukemic blasts from acute myeloid leukemia patients.
Tumor growth and metastasis formation are significantly reduced in animal experiments, suggesting valproic acid may serve as an effective drug for cancer therapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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