Thermo Fisher Scientific Valproic Acid Monoclonal Antibody (VP13-607.1.D5)
Valproic acid를 특이적으로 검출하는 단클론 항체로 ELISA에 최적화되어 있습니다. Mouse IgG1 형식이며 Protein G로 정제된 액상 제품입니다. 연구용으로 HDAC 억제 연구 및 항암 관련 연구에 활용 가능합니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VP13-607.1.D5 |
| Immunogen | Valproic acid, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1088196 |
Product Specific Information
MA1-10768 detects Valproic Acid.
MA1-10768 has been successfully used in ELISA applications.
The MA1-10768 immunogen is Valproic acid, conjugated to KLH.
Target Information
Valproic acid, valproate sodium, and divalproex belong to the group of anticonvulsant medicines used to control certain types of seizures in epilepsy treatment.
Valproic acid relieves histone deacetylase (HDAC)-dependent transcriptional repression and causes hyperacetylation of histones in cultured cells and in vivo. It inhibits HDAC activity in vitro, likely by binding to the catalytic center of HDACs.
Importantly, valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells, and leukemic blasts from acute myeloid leukemia patients. Tumor growth and metastasis formation are significantly reduced in animal experiments. Therefore, valproic acid may serve as an effective drug for cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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