Thermo Fisher Scientific Valproic Acid Monoclonal Antibody (VP10-201.7)
Valproic acid를 인식하는 mouse monoclonal antibody로 ELISA에 적합. 단백질 A로 정제된 액상 형태이며, PBS(pH 7.4) 용액에 보존제 없이 제공. -20°C에서 보관하며, 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VP10-201.7 |
| Immunogen | Valproic acid, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1088194 |
Product Specific Information
- MA1-10766 detects Valproic Acid.
- Validated for use in ELISA applications.
- Immunogen: Valproic acid conjugated to KLH.
Target Information
Valproic acid, valproate sodium, and divalproex are anticonvulsant compounds used to control certain types of seizures in epilepsy treatment.
Valproic acid relieves histone deacetylases (HDACs) dependent transcriptional repression, leading to hyperacetylation of histones in cultured cells and in vivo. It inhibits HDAC activity, likely by binding to the catalytic center of HDACs.
Furthermore, valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells, and leukemic blasts from acute myeloid leukemia patients. Tumor growth and metastasis formation are significantly reduced in animal models, suggesting potential use in cancer therapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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