Thermo Fisher Scientific DST Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DST. Recombinant protein control fragment (Product #RP-94902). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DST,uniProtId:Q03001-7,ncbiNodeId:9606,antigenRange:2614-2703,antigenLength:7570,antigenImageFileName:PA5-56396_DST_Q03001-7_Rabbit.svg,antigenImageFileNamePDP:PA5-56396_DST_Q03001-7_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640808

Product Specific Information

Immunogen sequence: KPRCQNVAED MDIQLCASIL NENSDENENI NTMILLDKMH SCSSLEKQQR VNVVQLASPS ENNLVTEKSN LPEYTTEIAG KSKENLLNHE

Highest antigen sequence identity to the following orthologs: Mouse - 33%, Rat - 33%.

Target Information

As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.