Thermo Fisher Scientific AGPS Polyclonal Antibody
Human AGPS 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로 AGPS 관련 대사 및 질환 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AGPS. Recombinant protein control fragment (Product #RP-95952). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637770 |
Product Specific Information
Immunogen sequence:
QIELTGKRYP LSGMGLPTFK EWIQNTLGVN VEHKTTSKAS LNPSDTPPSV VNEDFLHDLK ETNISYSQEA DDRVFRAHGH CLH
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 81%
Target Information
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family.
It encodes a protein that catalyzes the second step of ether lipid biosynthesis, converting acyl-dihydroxyacetonephosphate (DHAP) to alkyl-DHAP by adding a long-chain alcohol and removing a long-chain acid anion.
The protein localizes to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor.
Mutations in this gene are associated with rhizomelic chondrodysplasia punctata type 3 and Zellweger syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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