Thermo Fisher Scientific AMPK gamma-1 Polyclonal Antibody
AMPK gamma-1 단백질의 내인성 수준을 검출하는 Rabbit Polyclonal Antibody. Western blot과 ICC/IF에 적합하며 Human, Mouse, Rat 반응성. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로 에너지 대사 관련 연구에 활용 가능.
- 카탈로그번호
- PA5104369
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRKAG1, corresponding to a region within C-terminal amino acids |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853677 |
Product Specific Information
Antibody detects endogenous levels of total PRKAG1.
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
AMPK acts as an energy-sensing enzyme that monitors cellular energy status.
In response to metabolic stress, AMPK is activated and phosphorylates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis regulation.
This subunit represents one of the gamma regulatory components of AMPK.
Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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