Thermo Fisher Scientific COX5A Polyclonal Antibody
COX5A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COX5A (Accession P20674), corresponding to amino acid residues L23–G73 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853675 |
Product Specific Information
Antibody detects endogenous levels of total COX5A.
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that transfers electrons from cytochrome c to molecular oxygen, contributing to a proton electrochemical gradient across the inner mitochondrial membrane.
The complex consists of 13 mitochondrial- and nuclear-encoded subunits. Mitochondrially-encoded subunits perform electron transfer and proton pumping activities, while nuclear-encoded subunits may regulate and assemble the complex.
This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene, COX5AP1, is found on chromosome 14q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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