Thermo Fisher Scientific Phospho-eIF2b epsilon (Ser525) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human EIF2B5(Accession Q13144), corresponding to amino acid residues around phosphorylated Ser525. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:eIF2b epsilon,uniProtId:Q13144-1,ncbiNodeId:9606,antigenRange:525,antigenLength:721,antigenImageFileName:PA5-118668_eIF2b_epsilon_Q13144-1_Rabbit.svg,antigenImageFileNamePDP:PA5-118668_eIF2b_epsilon_Q13144-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2903168

Product Specific Information

Antibody detects endogenous levels of eIF2B epsilon only when phosphorylated at Ser525.

Target Information

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.