Thermo Fisher Scientific Phospho-eIF2b epsilon (Ser525) Polyclonal Antibody
Phospho-eIF2b epsilon (Ser525)을 인식하는 Rabbit Polyclonal 항체로, 인산화된 형태의 eIF2B epsilon 단백질 검출에 적합합니다. Western blot 및 IHC에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF2B5 (Accession Q13144), corresponding to amino acid residues around phosphorylated Ser525 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903168 |
Product Specific Information
Antibody detects endogenous levels of eIF2B epsilon only when phosphorylated at Ser525.
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (eIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis.
Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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