Thermo Fisher Scientific IGF2BP2 Monoclonal Antibody (OTI3F9), TrueMAB
IGF2BP2 단백질을 인식하는 Mouse Monoclonal Antibody로 다양한 응용 분야(WB, IHC, ICC/IF, Flow)에 사용 가능. 고순도 Affinity Chromatography 정제, Lyophilized 형태로 제공. Human 및 Dog 반응성, 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F9 |
| Immunogen | Full length human recombinant protein of human IGF2BP2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family, which recruits target transcripts to cytoplasmic protein-RNA complexes.
It contains four KH domains and two RRM domains, binding to the 5′ UTR of IGF2 mRNA to regulate its translation.
Alternate splice variants encoding different isoforms have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some hepatocellular carcinoma patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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