Thermo Fisher Scientific IGF2BP2 Monoclonal Antibody (OTI3C8), TrueMAB
IGF2BP2 단백질을 표적하는 Mouse IgG1 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용.
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Thermo Fisher Scientific IGF2BP2 Monoclonal Antibody (OTI3C8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C8 |
| Immunogen | Full length human recombinant protein of human IGF2BP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family that recruits target transcripts to cytoplasmic protein-RNA complexes.
It contains four KH domains and two RRM domains, and binds to the 5′ UTR of IGF2 mRNA to regulate its translation.
Alternate splice variants encoding different isoforms have been identified. Autoantibodies against IGF2BP2 have been detected in sera from some patients with hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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