Thermo Fisher Scientific IGF2BP2 Monoclonal Antibody (OTI6C4), TrueMAB
IGF2BP2 단백질을 인식하는 Mouse Monoclonal 항체로 Western blot, ICC/IF, Flow cytometry에 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 공급. PBS buffer에 trehalose 포함, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C4 |
| Immunogen | Full length human recombinant protein of human IGF2BP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family that recruits target transcripts to cytoplasmic protein-RNA complexes.
It contains four KH domains and two RRM domains, functioning by binding to the 5′ UTR of IGF2 mRNA and regulating IGF2 translation.
Alternate splice variants encoding different isoforms have been characterized.
Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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