Thermo Fisher Scientific PTX3 Monoclonal Antibody (MNB4), FITC
PTX3 단백질을 인식하는 마우스 단클론 항체(MNB4)로 FITC 형광 표지되어 있습니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. 498/517 nm 형광 특성으로 세포 및 조직 내 PTX3 검출에 활용 가능합니다.
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Thermo Fisher Scientific PTX3 Monoclonal Antibody (MNB4), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MNB4 |
| Immunogen | Human recombinant PTX3 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
Available Formats
- Unconjugated (Cat. MA5-49098)
- Custom conjugation available upon request
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. PTX3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor with a non-redundant role in resistance to selected microbial agents.
PTX3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. It binds selected pathogens including Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium.
PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells. Its secretion in adipose cells can be induced by TNF and is involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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