Thermo Fisher Scientific KCNN1 Polyclonal Antibody
KCNN1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 사용 가능. 인간 종에 반응하며, 동결 건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: 참고 문헌 보기
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: 참고 문헌 보기
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from N-terminal region of human KCNN1 (SK, SK1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: KCNN1.
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and influence neuronal firing patterns.
Each AHP component is kinetically distinct and mediated by different calcium-activated potassium channels.
The KCNN1-encoded protein is activated before membrane hyperpolarization and contributes to the slow component of synaptic AHP.
It forms a voltage-independent calcium-activated channel with calmodulin-binding subunits and is a member of the KCNN family of potassium channels.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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