Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI24A2), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms.
Mutations in the gene have been identified in aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been found for this gene.
Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally occurring transcripts (NME1-NME2), which encode a fusion protein comprised of sequences from both gene products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.