Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI3A12), TrueMAB
인간 KLK8 단백질(아미노산 33–260)을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화되어 있으며, 무보존제·동결건조 형태로 제공. 재구성 및 결합 실험에 적합하며 암 및 질환 바이오마커 연구용으로 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A12 |
| Immunogen | Human recombinant protein fragment (aa 33–260 of KLK8) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve ~1 mg/mL final concentration.
- For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological roles. Many are implicated in carcinogenesis and may serve as cancer or disease biomarkers.
KLK8 is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. It may be involved in proteolytic cascades in the skin and act as a biomarker for ovarian cancer. Multiple transcript variants exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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