Thermo Fisher Scientific TNFSF13B Monoclonal Antibody (OTI7F12), TrueMAB
BAFF 단백질을 인식하는 인간 반응성 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, 무보존제 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, B세포 활성화 연구에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 134–285 of human TNFSF13B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
BAFF (B-cell activating factor) is a membrane-bound cytokine expressed by B cell lineage cells.
The soluble form binds to TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR receptors.
It plays a crucial role in B cell proliferation and differentiation, and is also expressed by T lymphocytes, promoting T cell activation and survival.
Multiple isoforms resulting from alternative splicing and glycosylation have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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