Thermo Fisher Scientific PCBP1 Recombinant Rabbit Monoclonal Antibody (7Y8C5)
PCBP1 단백질을 인식하는 토끼 단클론성 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 높은 특이성과 재현성을 제공합니다. 인체 및 생쥐 시료에 반응하며, 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7Y8C5 |
| Immunogen | A synthetic peptide corresponding to amino acids 100–200 of human hnRNP E1/PCBP1 (NP_006187.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.087 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093867 |
Product Specific Information
Immunogen sequence:
LRLVVPATQC GSLIGKGGCK IKEIRESTGA QVQVAGDMLP NSTERAITIA GVPQSVTECV KQICLVMLET LSQSPQGRVM TIPYQPMPAS SPVICAGGQD R
Target Information
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. Along with PCBP-2 and hnRNPK, it corresponds to major cellular polydomains involved in RNA binding. This protein, together with PCBP-2, also functions as a translational coactivator of poliovirus RNA through sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure. It has also been implicated in translational control of 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. Additionally, it may play a role in forming a sequence-specific alpha-globin mRNP complex associated with alpha-globin mRNA stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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