Thermo Fisher Scientific CYP1A1 Recombinant Rabbit Monoclonal Antibody (2F7A2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:4,800

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2F7A2

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CYP1A1 (NP_000490.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYP1A1,uniProtId:P04798-1,ncbiNodeId:9606,antigenRange:250-350,antigenLength:512,antigenImageFileName:MA5-51451_CYP1A1_P04798-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51451_CYP1A1_P04798-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.09 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094300

Product Specific Information

Immunogen sequence: AFKDLNEKFY SFMQKMVKEH YKTFEKGHIR DITDSLIEHC QEKQLDENAN VQLSDEKIIN IVLDLFGAGF DTVTTAISWS LMYLVMNPRV QRKIQEELDT V

Target Information

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme`s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.