Thermo Fisher Scientific IL-18 Recombinant Rabbit Monoclonal Antibody (5L10S3)
IL-18에 특이적인 재조합 토끼 모노클로날 항체로, Western Blot, IHC, ELISA 등 다양한 응용에 적합함. 인간, 생쥐, 흰쥐에 반응하며 HEK293 세포에서 발현됨. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:28,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5L10S3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–193 of human IL-18 (NP_001553.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.77 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094251 |
Product Specific Information
Immunogen sequence:
MAAEPVEDNC INFVAMKFID NTLYFIAEDD ENLESDYFGK LESKLSVIRN LNDQVLFIDQ GNRPLFEDMT DSDCRDNAPR TIFIISMYKD SQPRGMAVTI SVKCEKISTL SCENKIISFK EMNPPDNIKD TKSDIIFFQR SVPGHDNKMQ FESSSYEGYF LACEKERDLF KLILKKEDEL GDRSIMFTVQ NED
Target Information
The protein encoded by this gene is a proinflammatory cytokine that induces IFN-gamma production in T cells. In combination with IL-12, it inhibits IL-4 dependent IgE and IgG1 production while enhancing IgG2a production in B cells. IL-18 binding protein can interact specifically with this cytokine to negatively regulate its biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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