Thermo Fisher Scientific ZIPK Polyclonal Antibody
ZIPK 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. DAPK3 신호전달 및 세포 사멸 연구에 활용 가능. Jurkat 또는 HeLa lysate를 양성 대조군으로 권장. -20°C 보관, 동결/해동 반복은 피해야 함.
- 카탈로그번호
- PA112521
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Suggested Positive Control: Jurkat or HeLa whole cell lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 279–298 of human ZIP kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1088350 |
Product Specific Information
A suggested positive control for this product is Jurkat or HeLa whole cell lysate.
Target Information
DAPK3 is a serine/threonine kinase functionally linked to cell motility, smooth muscle contractility, and cell death processes. DAPK3 is encoded by ZIPK and is a component of desmosomes and the epidermal cornified envelope in keratinocytes.
The N-terminal domain interacts with the plasma membrane, while the C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin, possibly linking the cornified envelope, desmosomes, and intermediate filaments.
AKT1/PKB, a kinase mediating cell growth and survival signaling, interacts with this protein, suggesting a potential role as a localization signal in AKT1-mediated signaling.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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