Thermo Fisher Scientific CD223 (LAG-3) Monoclonal Antibody (3DS223H), PE, eBioscience
인간 CD223(LAG-3)을 인식하는 3DS223H 단클론 항체로, Flow Cytometry용으로 최적화된 PE 결합형 제품입니다. T세포 활성 조절 연구에 적합하며, 고순도 친화 크로마토그래피 정제 및 포르말데히드 고정 항원 인식이 가능합니다.
- 카탈로그번호
- 12-2239-4x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD223 (LAG-3) Monoclonal Antibody (3DS223H), PE, eBioscience
Thermo Fisher Scientific CD223 (LAG-3) Monoclonal Antibody (3DS223H), PE, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.06 µg)/test
Publications: View 14 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3DS223H |
| Immunogen | hCD223-FC PFA 4% |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572596 |
Additional Formats
- Alexa Fluor 647
- Alexa Fluor 660
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Brilliant UV 395 / 563 / 661 / 737 / 805
- Brilliant Violet 421 / 480 / 605 / 650 / 711 / 786
- eFluor 450 / 506
- FITC
- NovaFluor Blue 510 / Blue 660-120S / Red 700 / Yellow 590 / Yellow 610 / Yellow 700 / Yellow 730
- PE-Cyanine5 / PE-Cyanine7 / PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436 / 600 / 645 / 702 / 780
- Request custom conjugation
Product Specific Information
This 3DS223H monoclonal antibody recognizes human CD223, also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein of the Ig superfamily with homology to CD4. It binds to MHC class II with higher affinity than CD4 and negatively regulates T cell activation and homeostatic proliferation.
Surface expression of LAG-3 occurs on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells express LAG-3 at higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b identifies human and mouse Type 1 regulatory T cells (Tr1 cells).
- Recognizes formaldehyde-fixed epitope
- Reported for flow cytometric analysis
- Tested on stimulated normal human peripheral blood cells
- Recommended use: 5 µL (0.06 µg) per test (100 µL final volume)
- Excitation: 488–561 nm; Emission: 578 nm; Laser: Blue, Green, Yellow-Green
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. It binds MHC class II with high affinity and plays a role in negative regulation of T cell activation and homeostatic proliferation. Expressed on activated T cells, regulatory T cells, and NK cells. CD8+ T cells typically express higher levels than CD4+ T cells. Coexpression with CD49b identifies Tr1 cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.