Thermo Fisher Scientific Human STING Synthetic Peptide
Human STING 단백질의 C-말단 17개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20782 항체의 차단 펩타이드로 사용 가능. NF-κB 및 IRF3 경로 활성화 연구에 활용. 정제된 액상 형태로 제공되며 PBS/BSA buffer에 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human MPYS.
PEP-0896 can be used as a blocking peptide with polyclonal antibody PA5-20782.
Target Information
STING is a 379 amino acid signaling protein that acts as an important component of innate immune signaling. It activates both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferons (IFN-alpha and IFN-beta), exerting a potent antiviral state.
STING may have translocon function influencing induction of type I interferons and is involved in apoptotic signal transduction via association with MHC-II, facilitating detection of intracellular viral RNA and B-form DNA. It mediates death signaling through ERK pathway activation.
STING is generally localized in endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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