Thermo Fisher Scientific Human CCDC134 Synthetic Peptide
인간 CCDC134 단백질의 N-말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20780의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며, PBS(pH 7.2)와 BSA를 포함합니다. 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human CCDC134.
PEP-0894 can be used as a blocking peptide with polyclonal antibody PA5-20780.
Target Information
The coiled-coil domain is a common protein motif often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments.
CCDC134 is a secretory protein that inhibits the transcriptional activity of the Elk1 protein. Overexpression of CCDC134 inhibits phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while siRNA against CCDC134 activates Elk1 transcriptional activity and phosphorylation of Erk and JNK/SAPK.
These findings suggest a potential inhibitory role of CCDC134 in MAPK-mediated Elk1 transcription.
CCDC134 is widely expressed in normal adult tissues, tumors, and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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