Thermo Fisher Scientific Human MAK10 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 19 amino acids near the amino terminus of human MAK10.
PEP-0897 can be used as a blocking peptide with polyclonal antibody PA5-20783.

Target Information

The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) highly conserved among vertebrates. It is expressed in various tissues in the developing rat embryo but restricted in expression in adults, remaining detectable only in tissues undergoing continual cell renewal or responding to pathological injury.
The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, partly through regulation of TOR signaling events. At least two isoforms of MAK10 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.