Thermo Fisher Scientific H2BK5ac Polyclonal Antibody
H2BK5ac에 특이적인 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 항체로 PBS+50% glycerol에 보관. For Research Use Only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human H2BFS (Accession P57053), corresponding to amino acid residues M1–G27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899327 |
Product Specific Information
Antibody detects endogenous levels of Acetyl-H2B only when acetylated at Lys5.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). These structures compact DNA into chromatin, limiting accessibility to transcription, replication, and repair machinery. Histones play central roles in transcription regulation, DNA repair, DNA replication, and chromosomal stability. H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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