Thermo Fisher Scientific FKBP5 Recombinant Rabbit Monoclonal Antibody (JB95-39)
FKBP5 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, IHC, Flow Cytometry에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제된 고순도 항체입니다. 인간 및 랫트 반응성으로 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB95-39 |
| Immunogen | Synthetic peptide within human FKBP51 aa 400–440 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2899010 |
Target Information
FKBP5 is a member of the immunophilin protein family, which plays a role in immunoregulation and cellular processes involving protein folding and trafficking. It functions as a cis-trans prolyl isomerase that binds to immunosuppressants FK506 and rapamycin, mediating calcineurin inhibition. FKBP5 interacts with mature hetero-oligomeric progesterone receptor complexes along with HSP90 and P23 proteins. The FKBP5 gene has multiple polyadenylation sites, and alternative splicing produces several transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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