Thermo Fisher Scientific alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (JE45-22)
Recombinant rabbit monoclonal antibody targeting alpha Actinin 2. Validated for WB and IHC applications with high specificity for human, mouse, and rat. Liquid form with 1 mg/mL concentration, purified by Protein A. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (predicted) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE45-22 |
| Immunogen | Recombinant protein within human Sarcomeric Alpha Actinin (aa 1–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2899019 |
Target Information
Alpha actinins belong to the spectrin gene superfamily, a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it binds actin to the membrane.
- In skeletal, cardiac, and smooth muscle cells, isoforms are localized to the Z-disc and analogous dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-41266_alpha_Actinin_2_P35609-1_Rabbit.svg, MA5-41266_alpha_Actinin_2_P35609-1_Rabbit_PDP.jpeg)
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