Thermo Fisher Scientific CaV3.2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1890-2030 of human CACNA1H (NP_066921.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaV3.2,uniProtId:O95180-1,ncbiNodeId:9606,antigenRange:1890-2030,antigenLength:2353,antigenImageFileName:PA5-120102_CaV3.2_O95180-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120102_CaV3.2_O95180-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.22 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913674

Product Specific Information

Positive test controls include: Mouse heart, Rat testis, Rat heart. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.

Immunogen sequence: SARRVDADRP PLPQESPGAR DAPNLVARKV SVSRMLSLPN DSYMFRPVVP ASAPHPRPLQ EVEMETYGAG TPLGSVASVH SPPAESCASL QIPLAVSSPA RSGEPLHALS PRGTARSPSL SRLLCRQEAV HTDSLEGKID S

Target Information

This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.