Thermo Fisher Scientific Calumenin Polyclonal Antibody
Calumenin 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. 인간 및 랫트 반응성. ICC/IF 및 ELISA에 사용 가능. 고순도 Affinity Chromatography 정제, -20°C 보관. 연구용으로 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–315 of human CALU (NP_0012101) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804978 |
Product Specific Information
Immunogen sequence:
KPTEKKDRVH HEPQLSDKVH NDAQSFDYDH DAFLGAEEAK TFDQLTPEES KERLGKIVSK IDGDKDGFVT VDELKDWIKF AQKRWIYEDV ERQWKGHDLN EDGLVSWEEY KNATYGYVLD DPDPDDGFNY KQMMVRDERR FKMADKDGDL IATKEEFTAF LHPEEYDYMK DIVVQETMED IDKNADGFID LEEYIGDMYS HDGNTDEPEW VKTEREQFVE FRDKNRDGKM DKEETKDWIL PSDYDHAEAE ARHLVYESDQ NKDGKLTKEE IVDKYDLFVG SQATDFGEAL VRHDEF
Positive Samples: H460, Rat liver
Cellular Location: Endoplasmic reticulum lumen, Melanosome, Sarcoplasmic reticulum lumen
Target Information
Calumenin is a 315 amino acid Ca²⁺-binding member of the CREC, EF-hand protein family. It is a secreted protein containing six Ca²⁺-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca²⁺, Calumenin interacts with serum amyloid P component (SAP) and may play a role in immunological defense and amyloidosis. Calumenin inhibits the vitamin K-dependent γ-carboxylation system and may be involved in thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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