Thermo Fisher Scientific ATP1B1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 65-240 of human ATP1B1 (NP_0016681) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ATP1B1,uniProtId:P05026-1,ncbiNodeId:9606,antigenRange:65-240,antigenLength:303,antigenImageFileName:PA5-88526_ATP1B1_P05026-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88526_ATP1B1_P05026-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.59 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804976

Product Specific Information

Immunogen sequence: KPTYQDRVAP PGLTQIPQIQ KTEISFRPND PKSYEAYVLN IVRFLEKYKD SAQRDDMIFE DCGDVPSEPK ERGDFNHERG ERKVCRFKLE WLGNCSGLND ETYGYKEGKP CIIIKLNRVL GFKPKPPKNE SLETYPVMKY NPNVLPVQCT GKRDEDKDKV GNVEYFGLGN SPGFPL; Positive Samples: U-251MG, Mouse brain, Mouse liver, Mouse kidney, Rat kidney, Rat brain; Cellular Location: Cell membrane, Single-pass type II membrane protein

Target Information

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.