Thermo Fisher Scientific Cardiac Troponin T Polyclonal Antibody
Cardiac Troponin T 단백질을 인식하는 염소 유래 다클론 항체. Western blot에 적합하며 인간, 마우스, 돼지 시료에서 반응. 액상 형태로 제공되며 0.5 mg/mL 농도. 연구용으로 심근 단백질 발현 및 심장 기능 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TERKSGKRQTERE (aa 204–216) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933619 |
Product Specific Information
- This antibody is expected to recognize all reported isoforms (NP_000355.2; NP_001001430.1; NP_001001431.1; NP_001001432.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion concentration changes and plays a crucial role in muscle function and myofibril formation. In humans, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression is influenced by heart failure, and mutations have been linked to familial hypertrophic and dilated cardiomyopathy. The gene undergoes alternative splicing, producing tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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