Thermo Fisher Scientific Cardiac Troponin T Polyclonal Antibody
심근 트로포닌 T 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간·마우스·돼지·랫트 반응성을 가집니다. Western blot 및 Peptide ELISA에 적합하며, 모든 알려진 cTnT isoform을 인식합니다. 액상 형태로 0.5 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific Cardiac Troponin T Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.03–0.1 µg/mL
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RNRINDNQKVSKT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933620 |
Product Specific Information
- Expected to recognize all reported isoforms (NP_000355.2; NP_001001430.1; NP_001001431.1; NP_001001432.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion changes and is crucial for muscle function and myofibril formation.
In humans, four cTnT isoforms are expressed developmentally. Expression levels are affected by heart failure. Mutations in the Cardiac Troponin T gene are linked to familial hypertrophic cardiomyopathy and dilated cardiomyopathy. The gene undergoes alternative splicing, producing multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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