Thermo Fisher Scientific CDC27 Recombinant Rabbit Monoclonal Antibody (7U5A3)
CDC27 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단클론 항체로, WB와 ELISA에 최적화됨. 인간 및 생쥐 반응성, HEK293 발현 시스템 사용. 액상 형태로 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDC27 Recombinant Rabbit Monoclonal Antibody (7U5A3)
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7U5A3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 702–824 of human CDC27 (UniProt: P30260) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911944 |
Product Specific Information
- Positive test controls: DU145, Mouse testis, Rat testis
- Target localization: Nucleus
- Immunogen sequence:
NPLCKFHRAS VLFANEKYKS ALQELEELKQ IVPKESLVYF LIGKVYKKLG QTHLALMNFS WAMDLDPKGA NNQIKEAIDK RYLPDDEEPI TQEEQIMGTD ESQESSMTDA DDTQLHAAES DEF
Target Information
The CDC27 gene encodes a protein that shares strong similarity with the yeast Cdc27 and Schizosaccharomyces pombe nuc2 proteins. It is a key component of the anaphase-promoting complex (APC), composed of eight conserved subunits in eukaryotic cells. APC facilitates cyclin B-ubiquitin conjugate formation, driving ubiquitin-mediated proteolysis of B-type cyclins. CDC27 and other APC members contain TPR domains, important for protein-protein interactions. It interacts with mitotic checkpoint proteins such as Mad2, p55CDC, and BUBR1, contributing to mitosis timing regulation. Alternative splicing generates multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-42803_CDC27_P30260-1_Rabbit.svg, MA5-42803_CDC27_P30260-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.