Thermo Fisher Scientific TRIM45 Monoclonal Antibody (OTI3G3), TrueMAB
TRIM45 단백질을 인식하는 Mouse monoclonal antibody로, IHC(P) 및 ICC/IF에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 사용 가능. MAPK 경로 연구 및 세포 기능 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 288–580 of human TRIM45 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TRIM45 is a member of the tripartite motif (TRIM) family and may act as a transcriptional repressor in the MAPK pathway.
Alternative splicing variants have been described. TRIM45 proteins are involved in cellular processes such as proliferation, differentiation, development, oncogenesis, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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