Thermo Fisher Scientific TRIM45 Monoclonal Antibody (OTI4F1), TrueMAB
TRIM45 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot 및 IHC(P) 실험에 적합. 인간 시료 반응성, 동결건조 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 연구용으로 MAPK 경로 관련 전사 억제 기능 연구에 활용 가능.
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Thermo Fisher Scientific TRIM45 Monoclonal Antibody (OTI4F1), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 288–580 of human TRIM45 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TRIM45 is a member of the tripartite motif (TRIM) protein family. It may function as a transcriptional repressor of the mitogen-activated protein kinase (MAPK) pathway.
Alternatively spliced transcript variants have been described.
TRIM45 proteins are involved in various cellular processes such as proliferation, differentiation, development, oncogenesis, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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