Thermo Fisher Scientific Mono-methyl-HIST1H2BC (Lys15) Polyclonal Antibody
Mono-methyl-HIST1H2BC (Lys15)에 특이적인 Rabbit Polyclonal Antibody로 인간 시료에 반응. Western blot, ICC/IF, ELISA 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 안정적인 PBS/glycerol buffer로 보관 용이.
- 카탈로그번호
- PA5144329
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:10–1:100
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of Mono-methyl-Lys (15) derived from Human Histone H2B type 1-C/E/F/G/I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3093650 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction.
The protein exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone belonging to the H2B family.
This variant lacks a polyA tail and instead contains a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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