Thermo Fisher Scientific 2-hydroxyisobutyryl-Histone H3 (Lys14) Polyclonal Antibody
2-hydroxyisobutyryl-Histone H3 (Lys14)에 특이적인 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF, ELISA, ChIP assay에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, -20°C 이하에서 보관 권장. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | |
| ELISA | Assay-dependent | |
| ChIP assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of 2-hydroxyisobutyryl-Lys (14) derived from Human Histone H3.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.28 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3093643 |
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways that either directly change chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the nucleosome core and can undergo several types of post-translational modification, such as methylation, acetylation, and phosphorylation, influencing cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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