Thermo Fisher Scientific Acetyl-HIST1H2BC (Lys85) Polyclonal Antibody
Histone H2B의 Lys85 아세틸화를 인식하는 Rabbit Polyclonal 항체. 인간 시료에 반응하며, ICC/IF, ELISA, ChIP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:1–1:10 | |
| ELISA | Assay-dependent | |
| ChIP assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of Acetyl-Lys (85) derived from Human Histone H2B type 1-C/E/F/G/I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.11 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3093645 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction into higher order structures. The protein also exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is part of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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