Thermo Fisher Scientific CDKN3 Monoclonal Antibody (OTI4D8), TrueMAB
CDKN3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. HEK293T에서 생산된 full-length human CDKN3 항원을 면역원으로 사용하였으며, carrier-free 형태로 제공되어 다양한 실험에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D8 |
| Immunogen | Full length human recombinant protein of human CDKN3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It acts as a cyclin-dependent kinase inhibitor that interacts with and dephosphorylates CDK2 kinase, preventing its activation. CDKN3 has been reported to be deleted, mutated, or overexpressed in various cancers. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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