
Thermo Fisher Scientific GBP1 Monoclonal Antibody (OTI1B2), TrueMAB
Human GBP1 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 최적화됨. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로만 사용 가능하며, 염증 및 세포 이동 관련 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Full length human recombinant protein of human GBP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
GBP1 (Guanlyate Binding Protein 1) is a 68 kDa GTPase and member of the GTPase1 family. Its expression is induced by interferon-gamma and inflammatory cytokines such as IL-1α, IL-1β, and TNF-α. GBP1 is also regulated by TLR pathway activation and NF-κB signaling. Functionally, GBP1 suppresses angiogenesis and migration, especially in endothelial cells, playing a key role in inflammatory and cell migration networks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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