Thermo Fisher Scientific PDHB Recombinant Rabbit Monoclonal Antibody (ARC1074)
Thermo Fisher Scientific의 PDHB Recombinant Rabbit Monoclonal Antibody (ARC1074)는 인간, 마우스, 랫트에 반응하는 재조합 단일클론 항체로, WB, IHC, ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 액상 형태이며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1074 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 260–359 of human Pyruvate Dehydrogenase E1 beta subunit (P11177) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.23 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849451 |
Product Specific Information
Immunogen sequence:
GVECEVINMR TIRPMDMETI EASVMKTNHL VTVEGGWPQF GVGAEICARI MEGPAFNFLD APAVRVTGAD VPMPYAKILE DNSIPQVKDI IFAIKKTLNI
Target Information
PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also known as PHE1B.
This mitochondrial enzyme is a component of the pyruvate dehydrogenase multienzyme complex (PDH) and catalyzes the first reaction of the oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO₂.
Defects in PDHB are associated with pyruvate dehydrogenase E1-beta deficiency (PDHBD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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