Thermo Fisher Scientific TPPP Recombinant Rabbit Monoclonal Antibody (ARC1129)
TPPP 단백질을 타겟으로 한 Thermo Fisher Scientific의 재조합 토끼 단클론 항체 ARC1129. Western blot, IHC, ELISA에 적합하며 높은 특이성과 재현성을 제공. HEK293 발현 시스템 기반, 액상 형태로 -20°C 보관.
- 판매단위
- pk
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Thermo Fisher Scientific TPPP Recombinant Rabbit Monoclonal Antibody (ARC1129)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1129 |
| Immunogen | Synthetic peptide corresponding to amino acids 100–200 of human TPPP/p25 (O94811) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849450 |
Product Specific Information
Immunogen sequence:
FSKIKGKSCR TITFEQFQEA LEELAKKRFK DKSSEEAVRE VHRLIEGKAP IISGVTKAIS SPTVSRLTDT TKFTGSHKER FDPSGKGKGK AGRVDLVDES G
Target Information
Tubulin family members are globular proteins essential for microtubule assembly, which play key roles in mitosis, cytokinesis, and vesicle transport.
TPPP (Tubulin polymerization-promoting protein), also known as p24/p25, is a 219-amino-acid protein localized in the perinuclear cytoplasm. It promotes tubulin polymerization into double-walled tubules and stabilizes microtubule structures.
Overexpression of TPPP disrupts mitotic spindle formation and nuclear envelope breakdown. It is phosphorylated by TPK II and encoded by a gene located on human chromosome 5.
TPPP may contribute to microtubule polymerization, bundling, and stabilization, maintaining microtubule network integrity and participating in mitotic spindle assembly.
Additional Information
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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