Thermo Fisher Scientific Phospho-CDK2 (Tyr15) Polyclonal Antibody
Human CDK2 (phospho Tyr15)에 특이적인 rabbit polyclonal antibody로 Western blot에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, 0.39 mg/mL 농도의 액상 형태. HeLa 세포에서 양성 대조 확인됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-CDK2 (Tyr15) Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CDK2 (phospho Tyr15). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736360 |
Product Specific Information
- Positive Control: HeLa
- Predicted Reactivity: Chicken (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene, which is localized exclusively in the nucleus. CyclinO shows significant uracil-DNA glycosylase activity.
CDK2/cyclinO protein levels increase during G1 phase and are turned over during the cell cycle. The levels of cyclin A–cdk2 are maximal at the G1/S transition, and both cdk2 and cyclin A are associated with DNA in the initiation complex during replication.
Rb protein acts as a substrate for cdk2–cyclin E and/or cdk2–cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1, S, and G2 phases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-77907_CDK2_P24941-1_Rabbit.svg, PA5-77907_CDK2_P24941-1_Rabbit_PDP.jpeg)
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