Thermo Fisher Scientific ALOX5 Polyclonal Antibody
ALOX5 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반, 액상 형태로 -20°C 보관. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ALOX5 (Accession P09917), corresponding to amino acid residues E643–I674 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899430 |
Product Specific Information
This antibody detects endogenous levels of total 5-Lipoxygenase.
Target Information
This gene encodes a protein which, together with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites implicated in various inflammatory responses such as asthma, arthritis, and psoriasis. This protein localizes to the plasma membrane. Inhibitors impede translocation of 5-lipoxygenase from the cytoplasm to the membrane, thereby inhibiting activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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