Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
CTHRC1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 사람과 생쥐에 반응하며 Western blot에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 연구용으로만 사용.
- 카탈로그번호
- A305-863A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 193 and 243 of human Collagen triple helix repeat-containing protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted reactivity by homology: Rat.
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration.
CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, where it plays a significant role in progression and metastasis by regulating tumor cell migration and adhesion. Overexpression can serve as an independent prognostic marker in gastric cancer. Mutations at this locus are associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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