Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (MEM-81)

Applications

• Flow Cytometry (Flow)

Tested Dilution: 1 µg/mL
Publications: -

Product Specifications

Product Specific Information

This antibody reacts with an extracellular epitope on human classical MHC Class I molecules in native cell-surface forms.
MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin.
They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense.
Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.